Phenotypes associated with this allele

• Allele Symbol: Tg(Kap-Ppara/AGT)562Dpo
• Allele Name: transgene insertion 562, Didier Portilla
• Allele ID: MGI:5319689
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Kap-Ppara/AGT)562Dpo/0	Not Specified	MGI:5319692

Genotype
MGI:5319692

tg1

• Allelic Composition: Tg(Kap-Ppara/AGT)562Dpo/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:172337 )

• improved survival following cisplatin exposure in mice pretreated with testosterone

renal/urinary system

abnormal kidney physiology ( J:172337 )

• decrease in cisplatin induced acute kidney injury in mice pretreated with testosterone

decreased susceptibility to kidney reperfusion injury ( J:172337 , J:183786 )

• in mice pretreated with testosterone (J:172337)

• in mice pretreated with testosterone the appearance of myofibroblasts is inhibited and interstitial fibrosis is reduced following unilateral ureteral obstruction (J:183786)

homeostasis/metabolism

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:172337 )

• improved survival following cisplatin exposure in mice pretreated with testosterone

decreased physiological sensitivity to xenobiotic ( J:172337 )

• decrease in cisplatin induced acute kidney injury in mice pretreated with testosterone

decreased susceptibility to kidney reperfusion injury ( J:172337 , J:183786 )

• in mice pretreated with testosterone (J:172337)

• in mice pretreated with testosterone the appearance of myofibroblasts is inhibited and interstitial fibrosis is reduced following unilateral ureteral obstruction (J:183786)