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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gnetm1.1Masn
targeted mutation 1.1, Masahide Asano
MGI:5320944
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gnetm1.1Masn/Gnetm1.1Masn involves: 129P2/OlaHsd * C57BL/6 MGI:5320971


Genotype
MGI:5320971
hm1
Allelic
Composition
Gnetm1.1Masn/Gnetm1.1Masn
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnetm1.1Masn mutation (0 available); any Gne mutation (49 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Kidney abnormalities in Gnetm1.1Masn/Gnetm1.1Masn mice

mortality/aging
• mice begin to die around 100 days and half of them have died by 500 days

renal/urinary system
• as early as 10 days of age
• at 3 and 6 months
• however, renal disorder is suppressed by administration of Neu5Ac
• in the interstitium at 6 and 12 months
• pale and irregularly shaped
• however, renal disorder is suppressed by administration of Neu5Ac
• flattened and fused at 4 months
• at 3 months
• severe at 6 and 12 months
• at P8, 3 months, 6 months and 12 months
• however, renal disorder is suppressed by administration of Neu5Ac
• due to impaired maintenance
• at 3 months
• at 6 and 12 months
• however, renal disorder is suppressed by administration of Neu5Ac

immune system
• in the interstitium at 6 and 12 months

homeostasis/metabolism
• as early as 10 days of age
• at 3 and 6 months
• however, renal disorder is suppressed by administration of Neu5Ac





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory