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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(MSV-SKI)33Hugh
transgene insertion, Simon M Hughes
MGI:5424888
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Acta1tm1Hrd/Acta1+
Tg(MSV-SKI)33Hugh/?
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6JArc) MGI:5425007


Genotype
MGI:5425007
cx1
Allelic
Composition
Acta1tm1Hrd/Acta1+
Tg(MSV-SKI)33Hugh/?
Genetic
Background
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6JArc)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acta1tm1Hrd mutation (1 available); any Acta1 mutation (16 available)
Tg(MSV-SKI)33Hugh mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mobility in open field tests is normal
• forearm grip strength is unaffected by presence of transgene
• mobility in open field tests is unaffected by presence of transgene

mortality/aging
• survival is not affected by the presence of the transgene

muscle
• increased myofiber size
• nemaline rod pathology is unaffected by presence of transgene





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory