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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lrp2tm3Tew
targeted mutation 3, Thomas E Willnow
MGI:5426261
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lrp2tm3Tew/Lrp2tm3Tew Not Specified MGI:5426262
ht2
 		Lrp2tm3Tew/Lrp2+ Not Specified MGI:5426263


Genotype
MGI:5426262
hm1
Allelic
Composition		 Lrp2tm3Tew/Lrp2tm3Tew
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp2tm3Tew mutation (0 available); any Lrp2 mutation (261 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, incomplete penetrance ( J:184259 )
• only about 5% ofhomozygotes survive to adulthood

nervous system




Genotype
MGI:5426263
ht2
Allelic
Composition		 Lrp2tm3Tew/Lrp2+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp2tm3Tew mutation (0 available); any Lrp2 mutation (261 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:184259 )
N
• no low level protein urea
• no defect in uptake of vitamin D-binding protein
• urinary electrolytes are normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory