All Phenotypes Airn<tm2.1Dpb> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Airn^tm2.1Dpb
targeted mutation 2.1, Denise P Barlow
MGI:5426385

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Airn^tm2.1Dpb/Airn^tm2.1Dpb	involves: 129S2/SvPas * 129S4/SvJaeSor * FVB/N	MGI:5426387

Allelic Composition	Airn^tm2.1Dpb/Airn^tm2.1Dpb
Genetic Background	involves: 129S2/SvPas * 129S4/SvJaeSor * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Airn^tm2.1Dpb mutation (0 available); any Airn mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:183397 )

N	• male fertility is normal

reduced female fertility ( J:183397 )

cellular

abnormal DNA methylation ( J:183397 )

• mice lack maternal methylation of the Airn promoter

maternal effect ( J:183397 )

• all offspring of female mice die in utero or within 2 days of birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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