All Phenotypes Pprc1<tm1Gning> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pprc1^tm1Gning
targeted mutation 1, Guang Ning
MGI:5426425

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pprc1^tm1Gning/Pprc1^tm1Gning	involves: C57BL/6	MGI:5426426

Allelic Composition	Pprc1^tm1Gning/Pprc1^tm1Gning
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pprc1^tm1Gning mutation (0 available); any Pprc1 mutation (98 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die between E3.5 and E6.5

embryo

abnormal germ layer development ( J:183886 )

• at E6.5, embryos fail to form clearly differentiated tissues unlike control mice

disorganized embryonic tissue ( J:183886 )

• at E5.5

inner cell mass degeneration ( J:183886 )

• following hatching

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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