All Phenotypes Dll1<tm1.1Hri> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dll1^tm1.1Hri
targeted mutation 1.1, Palle Serup
MGI:5426508

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Dll1^tm1.1Hri/Dll1^tm1.1Hri Foxa2^{tm3.1(icre)Heli}/Foxa2⁺	involves: 129P2/OlaHsd * C57BL/6 * SJL	MGI:5428768

Allelic Composition	Dll1^tm1.1Hri/Dll1^tm1.1Hri Foxa2^{tm3.1(icre)Heli}/Foxa2⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll1^tm1.1Hri mutation (0 available); any Dll1 mutation (46 available)
Foxa2^{tm3.1(icre)Heli} mutation (0 available); any Foxa2 mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal pancreas development ( J:184814 )

• at E10.5, an excessive formation of glucagon +ve cells is observed

• reduced numbers of Nkx6-1+ve Ptf1a-ve cells are detected at E12.5

• however, no apparent defects in proximal-distal patterning in E15.5 and E18.5 embryos are observed

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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