All Phenotypes Bdnf<tm1.1Krj> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Bdnf^tm1.1Krj
targeted mutation 1.1, Kevin R Jones
MGI:5427360

Summary

2 genotypes

Allelic Composition	Bdnf^tm1.1Krj/Bdnf^tm1.1Krj
Genetic Background	involves: 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bdnf^tm1.1Krj mutation (0 available); any Bdnf mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

• at E13, female mice exhibit very few sensory neurons associated with the mammary gland rudiments unlike wild-type mice

endocrine/exocrine glands

• at E13, female mice exhibit very few sensory neurons associated with the mammary gland rudiments unlike wild-type mice

integument

• at E13, female mice exhibit very few sensory neurons associated with the mammary gland rudiments unlike wild-type mice

Allelic Composition	Bdnf^tm1.1Krj/Bdnf⁺
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bdnf^tm1.1Krj mutation (0 available); any Bdnf mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:184139 )

N	• whole apical and basal spine density in the visual cortex is normal at 3 weeks of age • distal segment density of both basal and apical dendrites is normal at 4 months of age

• spine head diameter fails to increase as it does in controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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