Phenotypes associated with this allele

• Allele Symbol: Adamts1^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:5427602
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adamts1^tm1Dgen/Adamts1^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6J	MGI:5427736

Genotype
MGI:5427736

hm1

• Allelic Composition: Adamts1^tm1Dgen/Adamts1^tm1Dgen
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

abnormal kidney morphology ( J:82809 )

• discolored, 49 day homozygous mutant male

enlarged kidney ( J:82809 )

• enlarged and fluid-filled, 49 day homozygous mutant females and males

increased kidney weight ( J:82809 )

• weight and/or organ weight/body weight ratio increased, 49 day homozygous mutant females and males

kidney cortex atrophy ( J:82809 )

• cortex atrophic, 49 day homozygous females and males

hydronephrosis ( J:82809 )

• pelvis dilated, bilateral, 49 day homozygous females and males; unilateral, 49 day homozygous female

growth/size/body

enlarged kidney ( J:82809 )

• enlarged and fluid-filled, 49 day homozygous mutant females and males

increased kidney weight ( J:82809 )

• weight and/or organ weight/body weight ratio increased, 49 day homozygous mutant females and males