Analysis Tools|
Allele Symbol Allele Name Allele ID |
Mecp2tm1.1Mitoh targeted mutation 1.1, Masayuki Itoh MGI:5427621 |
||||||||||||||||
| Summary |
3 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
 |
• fewer mice are born when this allele is inherited maternally
• however, birth rates are normal when this allele is inherited paternally
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Placentas of embryos carrying a maternal Mecp2tm1.1Mitoh allele exhibit increased apoptosis
|
|
• fewer mice are born when this allele is inherited maternally
• however, birth rates are normal when this allele is inherited paternally
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
|
|
• when this allele is inherited maternally
|
|
N |
• mice do not exhibit any RTT-associated neurological phenotypes
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Placentas of embryos carrying a maternal Mecp2tm1.1Mitoh allele exhibit increased apoptosis
 |
• fewer mice are born when this allele is inherited maternally
• however, birth rates are normal when this allele is inherited paternally
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
|
|
• when this allele is inherited maternally
|
|
N |
• mice do not exhibit any RTT-associated neurological phenotypes
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
|
|
|
||
