Analysis Tools|
Allele Symbol Allele Name Allele ID |
Mecp2tm1.1Mitoh targeted mutation 1.1, Masayuki Itoh MGI:5427621 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
 |
• fewer mice are born when this allele is inherited maternally
• however, birth rates are normal when this allele is inherited paternally
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|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Placentas of embryos carrying a maternal Mecp2tm1.1Mitoh allele exhibit increased apoptosis
|
|
• fewer mice are born when this allele is inherited maternally
• however, birth rates are normal when this allele is inherited paternally
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
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• when this allele is inherited maternally
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N |
• mice do not exhibit any RTT-associated neurological phenotypes
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Placentas of embryos carrying a maternal Mecp2tm1.1Mitoh allele exhibit increased apoptosis
 |
• fewer mice are born when this allele is inherited maternally
• however, birth rates are normal when this allele is inherited paternally
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
|
|
• when this allele is inherited maternally
|
|
N |
• mice do not exhibit any RTT-associated neurological phenotypes
|
|
|
• when this allele is inherited maternally, E13.5 mice exhibit increased apoptosis compared with control mice
• however, mice do not exhibit increased apoptosis when this allele is paternally inherited
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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