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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adgrg1tm1Dgen
targeted mutation 1, Deltagen
MGI:5427671
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adgrg1tm1Dgen/Adgrg1tm1Dgen involves: 129P2/OlaHsd * C57BL/6J MGI:5427823


Genotype
MGI:5427823
hm1
Allelic
Composition		 Adgrg1tm1Dgen/Adgrg1tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgrg1tm1Dgen mutation (2 available); any Adgrg1 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal locomotor behavior ( J:82809 )
• homozygous mutants displayed a higher average velocity than wild-type in the open field test
decreased thermal nociceptive threshold ( J:82809 )
• homozygous mutants displayed shorter response latencies in the hot plate test

nervous system
abnormal cerebellar cortex morphology ( J:82809 )
• cerebellum, cortical malformation, homozygous mutants in 49 and 300 day cohorts




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory