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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pde4btm1Dgen
targeted mutation 1, Deltagen
MGI:5427687
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pde4btm1Dgen/Pde4btm1Dgen involves: 129P2/OlaHsd * C57BL/6J MGI:5427850


Genotype
MGI:5427850
hm1
Allelic
Composition		 Pde4btm1Dgen/Pde4btm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde4btm1Dgen mutation (2 available); any Pde4b mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
brain vacuoles ( J:82809 )
• vacuolization, homozygous females and males in cerebrum, cerebellum and brainstem
abnormal spinal cord morphology ( J:82809 )
• vacuolization, homozygous females and males




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory