About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pax2tm1.1Gdr
targeted mutation 1.1, Gregory R Dressler
MGI:5427892
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pax2tm1.1Gdr/Pax2tm1.1Gdr involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5427899
ht2
 		Pax2tm1Gdr/Pax2tm1.1Gdr involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5427900


Genotype
MGI:5427899
hm1
Allelic
Composition		 Pax2tm1.1Gdr/Pax2tm1.1Gdr
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax2tm1.1Gdr mutation (1 available); any Pax2 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

renal/urinary system
abnormal kidney development ( J:184878 )
• E10.5 kidney epithelial cells exhibit loss of polarity compared with wild-type cells

nervous system




Genotype
MGI:5427900
ht2
Allelic
Composition		 Pax2tm1Gdr/Pax2tm1.1Gdr
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax2tm1.1Gdr mutation (1 available); any Pax2 mutation (44 available)
Pax2tm1Gdr mutation (1 available); any Pax2 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

renal/urinary system
abnormal kidney development ( J:184878 )
• mice have very rudimentary kidneys at birth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory