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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mir34atm1.1Kry
targeted mutation 1.1, Gerard Karsentry
MGI:5427918
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Mir34atm1.1Kry/Mir34atm1.1Kry
Mirc21tm1.1Kry/Mirc21tm1.1Kry
Tg(Col1a1-cre)1Kry/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N MGI:5427926


Genotype
MGI:5427926
cn1
Allelic
Composition
Mir34atm1.1Kry/Mir34atm1.1Kry
Mirc21tm1.1Kry/Mirc21tm1.1Kry
Tg(Col1a1-cre)1Kry/0
Genetic
Background
involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir34atm1.1Kry mutation (0 available); any Mir34a mutation (9 available)
Mirc21tm1.1Kry mutation (0 available); any Mirc21 mutation (5 available)
Tg(Col1a1-cre)1Kry mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Increased bone mass in Mir34atm1.1Kry/Mir34atm1.1Kry Mirc21tm1.1Kry/Mirc21tm1.1Kry Tg(Col1a1-cre)1Kry/0 mice

skeleton
N
• osteoclast surface is normal
• at 3 months
• increased bone formation rate





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory