Analysis Tools
normal phenotype
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• mutant mice are viable to adulthood
• mice did not have alterations in heart weight/body weight or heart weight/ tibia length compared with control mice
• histological observations as well as expression of fetal gene and fibrotic markers were also similar to control mice
• mice have normal cardiac function, chamber size, and wall thickness compared with their littermate controls
• no changes in vessel volume in mutant mice
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