All Phenotypes Fcgr4<tm1.1Rav> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fcgr4^tm1.1Rav
targeted mutation 1.1, Jeffrey V Ravetch
MGI:5428684

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fcgr4^tm1.1Rav/Fcgr4^tm1.1Rav	involves: C57BL/6	MGI:5428687

Allelic Composition	Fcgr4^tm1.1Rav/Fcgr4^tm1.1Rav
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcgr4^tm1.1Rav mutation (0 available); any Fcgr4 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Decreased susceptibility to induced arthritis in Fcgr4^tm1.1Rav/Fcgr4^tm1.1Rav mice

immune system

immune system phenotype ( J:167375 )

N	• mice exhibit normal IgG-dependent Arthus and IgE-dependent passive cutaneous anaphylaxis reaction

• in a KBxN model

homeostasis/metabolism

• mice are protected from IgG-dependent induced nephrotoxic nephritis

skeleton

• in a KBxN model

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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