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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(ACTA1-SSPN)3.0Rcros
transgene insertion 3.0, Rachelle H Crosbie-Watson
MGI:5428721
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Dmdmdx/Dmdmdx
Tg(ACTA1-SSPN)3.0Rcros/0 		involves: C57BL/10ScSn MGI:5428739


Genotype
MGI:5428739
cx1
Allelic
Composition		 Dmdmdx/Dmdmdx
Tg(ACTA1-SSPN)3.0Rcros/0
Genetic
Background		 involves: C57BL/10ScSn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmdmdx mutation (31 available); any Dmd mutation (154 available)
Tg(ACTA1-SSPN)3.0Rcros mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal sarcolemma morphology ( J:185346 )
• dystrophic pathology observed in Dmdmdx mice is ameliorated with a decrease in centrally localized nuclei in skeletal muscles and reduced sarcolemmal membrane damage
centrally nucleated skeletal muscle fibers ( J:185346 )
• dystrophic pathology observed in Dmdmdx mice is ameliorated with a decrease in centrally localized nuclei in skeletal muscles and reduced sarcolemmal membrane damage
dystrophic muscle ( J:185346 )
• dystrophic pathology observed in Dmdmdx mice is ameliorated with a decrease in centrally localized nuclei in skeletal muscles and reduced sarcolemmal membrane damage




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory