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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ctnnb1tm1Wvv
targeted mutation 1, Wendy van Veelen
MGI:5430602
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Apctm1Rsmi/Apc+
Ctnnb1tm1Wvv/Ctnnb1+
Tg(Fabp1-cre)1Jig/? 		involves: 129P2/OlaHsd * C57BL/6J * FVB/N MGI:5430612


Genotype
MGI:5430612
cn1
Allelic
Composition		 Apctm1Rsmi/Apc+
Ctnnb1tm1Wvv/Ctnnb1+
Tg(Fabp1-cre)1Jig/?
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Rsmi mutation (1 available); any Apc mutation (158 available)
Ctnnb1tm1Wvv mutation (0 available); any Ctnnb1 mutation (49 available)
Tg(Fabp1-cre)1Jig mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased gastrointestinal tumor incidence ( J:185942 )
• significantly increased tumor load in the intestine of males but not females compared to heterozygous Apctm1Ecrm
• tumors in both the ilium and colon but smaller in size than in heterozygous Apctm1Ecrm

digestive/alimentary system
increased gastrointestinal tumor incidence ( J:185942 )
• significantly increased tumor load in the intestine of males but not females compared to heterozygous Apctm1Ecrm
• tumors in both the ilium and colon but smaller in size than in heterozygous Apctm1Ecrm




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory