Phenotypes associated with this allele

• Allele Symbol: Tg(Gucy2g-cre,-EGFP)52Irod
• Allele Name: transgene insertion 52, Ivan Rodriguez
• Allele ID: MGI:5430756
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Nrp1^tm2Ddg/Nrp1^tm2.1Ddg Tg(Gucy2g-cre,-EGFP)52Irod/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	MGI:5431517

Genotype
MGI:5431517

cn1

• Allelic Composition: Nrp1^tm2Ddg/Nrp1^tm2.1Ddg; Tg(Gucy2g-cre,-EGFP)52Irod/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:185650 )

N • in the olfactory bulb, Grueneberg glomeruli formation is not affected and their exclusion from guanylate cyclase G (GC-G) glomeruli is not affected

abnormal accessory olfactory bulb morphology ( J:185650 )

• numbers of Grueneberg axonal bundles consisting of multiple axons do not avoid the accessory olfactory bulb as seen in control animals; axonal fibers and microglomeruli cross bulb from medial to lateral side

• some Grueneberg fibers end deep into the vomeronasal glomeruli primarily in rostral part (not seen in controls)

• Grueneberg glomeruli form normally in mice with specific Nrp2 deletion and Grueneberg axons lacking Nrp2 do not cross the accessory olfactory bulb