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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ephb6/Trpv6tm1.1Mfre
targeted mutation 1.1, Marc Freichel
MGI:5430762
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ephb6/Trpv6tm1.1Mfre/Ephb6/Trpv6tm1.1Mfre involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N MGI:5430767


Genotype
MGI:5430767
hm1
Allelic
Composition
Ephb6/Trpv6tm1.1Mfre/Ephb6/Trpv6tm1.1Mfre
Genetic
Background
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ephb6/Trpv6tm1.1Mfre mutation (0 available); any Trpv6 mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• reduced percentage of viable sperm in the cauda epididymis

reproductive system
N
• female mice exhibit normal fertility
• mice exhibit normal testis size and male germ cell meiosis
• reduced percentage of viable sperm in the cauda epididymis
• impaired calcium absorption with increased calcium in the epididymal fluid
• when using male sperm for in vitro fertilization
• when using male sperm for in vitro fertilization

growth/size/body
N
• mice exhibit exhibit no growth defects





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory