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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Myh6-Med13)1Eno
transgene insertion 1, Eric N Olson
MGI:5431514
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Lepob/Lepob
Tg(Myh6-Med13)1Eno/0
involves: C57BL/6 MGI:5431521
tg2
Tg(Myh6-Med13)1Eno/0 B6.Cg-Tg(Myh6-Med13)1Eno MGI:5431520


Genotype
MGI:5431521
cx1
Allelic
Composition
Lepob/Lepob
Tg(Myh6-Med13)1Eno/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepob mutation (5 available); any Lep mutation (21 available)
Tg(Myh6-Med13)1Eno mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• compared with Lepob homozygotes

homeostasis/metabolism
• compared with Lepob homozygotes




Genotype
MGI:5431520
tg2
Allelic
Composition
Tg(Myh6-Med13)1Eno/0
Genetic
Background
B6.Cg-Tg(Myh6-Med13)1Eno
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• mice exhibit normal body temperature
• in male and female mice fed a high fat diet
• male mice fed a high fat diet fail to exhibit an increase in serum cholesterol unlike wild-type mice
• in male mice fed standard chow
• in male mice fed standard chow
• male mice fed a high fat diet exhibit improved glucose tolerance compared with wild-type mice
• male mice fed a high fat diet fail to exhibit an increase in hepatic triglyceride unlike wild-type mice

liver/biliary system
• male mice fed a high fat diet fail to exhibit an increase in hepatic triglyceride unlike wild-type mice

adipose tissue
• whether fed normal chow or a high fat diet, male mice exhibit decreased visceral white adipose tissue compared with wild-type mice
• in male mice fed normal chow or a high fat diet
• in mice at 7 and 12 months of age when fed normal chow
• whether fed normal chow or a high fat diet, male mice exhibit decreased subscapular brown adipose tissue compared with wild-type mice
• whether fed normal chow or a high fat diet, male mice exhibit decreased subscapular brown adipose tissue compared with wild-type mice

growth/size/body
• in male mice fed normal chow or a high fat diet
• in male and female mice fed a high fat diet





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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory