All Phenotypes Sptbn1<tm1.1Mnr> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sptbn1^tm1.1Mnr
targeted mutation 1.1, Matthew N Rasband
MGI:5431637

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Sptbn1^tm1.1Mnr/Sptbn1^tm1.1Mnr Tg(Nes-cre)1Kln/0	involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL	MGI:5431704

Allelic Composition	Sptbn1^tm1.1Mnr/Sptbn1^tm1.1Mnr Tg(Nes-cre)1Kln/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sptbn1^tm1.1Mnr mutation (1 available); any Sptbn1 mutation (139 available)
Tg(Nes-cre)1Kln mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:186168 )

• most mice die by P14

• however, some mice survive for more than 5 months

nervous system

abnormal axon initial segment morphology ( J:186168 )

• severely disrupted

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24