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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Azgp1tm1.1Sbah
targeted mutation 1.1, Seiamak Bahram
MGI:5431920
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Azgp1tm1.1Sbah/Azgp1tm1.1Sbah involves: 129P2/OlaHsd * C57BL/6 MGI:5431925


Genotype
MGI:5431925
hm1
Allelic
Composition		 Azgp1tm1.1Sbah/Azgp1tm1.1Sbah
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Azgp1tm1.1Sbah mutation (1 available); any Azgp1 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:118213 )
• when fed standard food or a high fat diet
enlarged spleen ( J:118213 )
• in mice fed a high fat diet

adipose tissue
abnormal adipose tissue physiology ( J:118213 )
• adipocytes stimulated with forskolin, IBMX, isoprenaline or CL316243 exhibit impaired lipolysis compared with wild-type cells

homeostasis/metabolism
impaired lipolysis ( J:118213 )
• in adipocytes stimulated with forskolin, IBMX, isoprenaline or CL316243

hematopoietic system
enlarged spleen ( J:118213 )
• in mice fed a high fat diet

immune system
enlarged spleen ( J:118213 )
• in mice fed a high fat diet




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory