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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm2(EGFP/cre)Alj
targeted mutation 2, Alexandra L Joyner
MGI:5432030
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm2(EGFP/cre)Alj
Pgbd5tm1.1Aken/Pgbd5tm1.1Aken 		involves: 129 * C57BL/6J * C57BL/6NTac * SW MGI:7616743


Genotype
MGI:7616743
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm2(EGFP/cre)Alj
Pgbd5tm1.1Aken/Pgbd5tm1.1Aken
Genetic
Background		 involves: 129 * C57BL/6J * C57BL/6NTac * SW
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Smo/EYFP)Amc mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
Gt(ROSA)26Sortm2(EGFP/cre)Alj mutation (2 available); any Gt(ROSA)26Sor mutation (993 available)
Pgbd5tm1.1Aken mutation (1 available); any Pgbd5 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased medulloblastoma incidence ( J:346387 )
• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele

nervous system
increased medulloblastoma incidence ( J:346387 )
• develop tumors with a similar latency to mice with one wild-type Pgbd5 allele, but most tumors retain an unrecombined floxed Pgbd5 allele




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory