cardiovascular system
• after more than 50 days of tamoxifen treatment, mice treated with L-NAME fail to exhibit an increase in systolic blood pressure compared with wild-type mice
|
hypertension
(
J:186053
)
• in tamoxifen-treated mice
|
• in tamoxifen-treated mice
|
• after more than 50 days of tamoxifen treatment, mice lose aortic relaxation induced by NO, carbachol or sildenafil unlike control mice
• however, mice exhibit normal relaxation in response to 8-Br-cGMP or atrial natriuretic peptide
|
muscle
• after more than 50 days of tamoxifen treatment, mice lose aortic relaxation induced by NO, carbachol or sildenafil unlike control mice
• however, mice exhibit normal relaxation in response to 8-Br-cGMP or atrial natriuretic peptide
|