mortality/aging
• only 2 homozygous embryos out of 29 present at E12.5
• multisystem organ hypoplasia and delayed development
|
embryo
growth/size/body
digestive/alimentary system
• organ hypoplasia and delayed development
|
liver/biliary system
• organ hypoplasia and delayed development
|
respiratory system
• organ hypoplasia and delayed development
|
skeleton
• organ hypoplasia and delayed development
|
vision/eye
• organ hypoplasia and delayed development
|