immune system
• across all times of stimulation and doses of agonist, neutrophils exhibit reduced reactive oxygen species production compared with wild-type cells
• PMA-stimulated neutrophils exhibit increased reactive oxygen species production compared with wild-type cells
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• fewer neutrophils migrate on glass and fibrinogen-coated glass in response to fMLP compared with wild-type cells
• however, migration into an aseptically inflamed peritoneum is normal
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cellular
• fewer neutrophils migrate on glass and fibrinogen-coated glass in response to fMLP compared with wild-type cells
• however, migration into an aseptically inflamed peritoneum is normal
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hematopoietic system
• across all times of stimulation and doses of agonist, neutrophils exhibit reduced reactive oxygen species production compared with wild-type cells
• PMA-stimulated neutrophils exhibit increased reactive oxygen species production compared with wild-type cells
|
• fewer neutrophils migrate on glass and fibrinogen-coated glass in response to fMLP compared with wild-type cells
• however, migration into an aseptically inflamed peritoneum is normal
|