mortality/aging
N |
• mice exhibit normal prenatal and postnatal survival
|
Allele Symbol Allele Name Allele ID |
Foxp4tm2.1Eem targeted mutation 2.1, Edward E Morrisey MGI:5433099 |
||||||||||||||||
Summary |
3 genotypes
|
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• mice exhibit normal prenatal and postnatal survival
|
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mice die within minutes of birth of apparent respiratory distress
|
• in the proximal airways at E18.5
|
• as determined by marker expression, mice exhibit an increase in ciliated epithelial cell differentiation compared with control mice
|
• at birth
|
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mice exhibit an increase in goblet cell differentiation compared with control mice
|
• following naphthalene injury, mice exhibit defective epithelial regeneration by ectopically activating goblet cell fate compared with control mice
|
• following naphthalene injury, mice exhibit defective epithelial regeneration by ectopically activating goblet cell fate compared with control mice
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|