Phenotypes associated with this allele

• Allele Symbol: Chn2^tm1.1Alk
• Allele Name: targeted mutation 1.1, Alex L Kolodkin
• Allele ID: MGI:5433303
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chn2^tm1.1Alk/Chn2^tm1.1Alk	involves: C57BL/6 * CD-1 * FVB/N	MGI:5433307

Genotype
MGI:5433307

hm1

• Allelic Composition: Chn2^tm1.1Alk/Chn2^tm1.1Alk
• Genetic Background: involves: C57BL/6 * CD-1 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon pruning ( J:186252 )

• infrapyramidal tract neurons exhibit impaired pruning compared with wild-type cells

• however, presynaptic pruning is largely normal

abnormal hippocampus development ( J:186252 )

• at P45, the infrapyramidal tract is longer than in wild-type mice

cellular

abnormal axon pruning ( J:186252 )

• infrapyramidal tract neurons exhibit impaired pruning compared with wild-type cells

• however, presynaptic pruning is largely normal