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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cbx3tm1Pbs
targeted mutation 1, Prim B Singh
MGI:5433765
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cbx3tm1Pbs/Cbx3tm1Pbs involves: 129 MGI:5433851


Genotype
MGI:5433851
hm1
Allelic
Composition		 Cbx3tm1Pbs/Cbx3tm1Pbs
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbx3tm1Pbs mutation (1 available); any Cbx3 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:186901 )
• despite Mendelian numbers at E19, fewer than expected adults are generated

reproductive system
reproductive system phenotype ( J:186901 )
N
• female mice exhibit normal reproductive system morphology
small testis ( J:186901 )
• severe
abnormal spermatogenesis ( J:186901 )
• severely impaired
• however, the number of gonocytes is normal
oligozoospermia ( J:186901 )
• very few mature sperm are detected

endocrine/exocrine glands
small testis ( J:186901 )
• severe

cellular
oligozoospermia ( J:186901 )
• very few mature sperm are detected




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory