About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Batf2tm1Kmm
targeted mutation 1, Kenneth Murphy
MGI:5435553
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Batf2tm1Kmm/Batf2tm1Kmm 129S6/SvEvTac-Batf2tm1Kmm MGI:5435558
cx2
 		Agtpbp1pcd-9J/Agtpbp1pcd-9J
Batf2tm1Kmm/Batf2tm1Kmm 		involves: 129S1/SvImJ * 129S6/SvEvTac MGI:5819377


Genotype
MGI:5435558
hm1
Allelic
Composition		 Batf2tm1Kmm/Batf2tm1Kmm
Genetic
Background		 129S6/SvEvTac-Batf2tm1Kmm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Batf2tm1Kmm mutation (1 available); any Batf2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to parasitic infection induced morbidity/mortality ( J:101977 )
• decreased survival after infection by Toxoplasma gondi.

mortality/aging
increased susceptibility to parasitic infection induced morbidity/mortality ( J:101977 )
• decreased survival after infection by Toxoplasma gondi.




Genotype
MGI:5819377
cx2
Allelic
Composition		 Agtpbp1pcd-9J/Agtpbp1pcd-9J
Batf2tm1Kmm/Batf2tm1Kmm
Genetic
Background		 involves: 129S1/SvImJ * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1pcd-9J mutation (1 available); any Agtpbp1 mutation (66 available)
Batf2tm1Kmm mutation (1 available); any Batf2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
ataxia ( J:238395 )
• homozygotes develop slight ataxia by 5 weeks of age and severe ataxia by 6 weeks of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory