All Phenotypes Spred1<tm1.1Ayos> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Spred1^tm1.1Ayos
targeted mutation 1.1, Akihiko Yoshimura
MGI:5436575

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spred1^tm1.1Ayos/Spred1^tm1.1Ayos	involves: 129 * C57BL/6 * SJL	MGI:5436576

Allelic Composition	Spred1^tm1.1Ayos/Spred1^tm1.1Ayos
Genetic Background	involves: 129 * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spred1^tm1.1Ayos mutation (1 available); any Spred1 mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased mast cell degranulation ( J:186742 )

• IgE-mediated degranulation is slightly higher than in control mice

increased mast cell number ( J:186742 )

• in the subcutaneous tissue

craniofacial

craniofacial phenotype ( J:186742 )

N	• mice exhibit normal snout size unlike in null mice

hematopoietic system

increased mast cell degranulation ( J:186742 )

• IgE-mediated degranulation is slightly higher than in control mice

increased mast cell number ( J:186742 )

• in the subcutaneous tissue

cellular

increased mast cell degranulation ( J:186742 )

• IgE-mediated degranulation is slightly higher than in control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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