All Phenotypes Spred1<tm1.1Ayos> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Spred1^tm1.1Ayos
targeted mutation 1.1, Akihiko Yoshimura
MGI:5436575

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spred1^tm1.1Ayos/Spred1^tm1.1Ayos	involves: 129 * C57BL/6 * SJL	MGI:5436576

Allelic Composition	Spred1^tm1.1Ayos/Spred1^tm1.1Ayos
Genetic Background	involves: 129 * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spred1^tm1.1Ayos mutation (1 available); any Spred1 mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased mast cell degranulation ( J:186742 )

• IgE-mediated degranulation is slightly higher than in control mice

increased mast cell number ( J:186742 )

• in the subcutaneous tissue

craniofacial

craniofacial phenotype ( J:186742 )

N	• mice exhibit normal snout size unlike in null mice

hematopoietic system

increased mast cell degranulation ( J:186742 )

• IgE-mediated degranulation is slightly higher than in control mice

increased mast cell number ( J:186742 )

• in the subcutaneous tissue

cellular

increased mast cell degranulation ( J:186742 )

• IgE-mediated degranulation is slightly higher than in control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24