Phenotypes associated with this allele

• Allele Symbol: Lrp1^b2b1554Clo
• Allele Name: Bench to Bassinet Program (B2B/CVDC), mutation 1554 Cecilia Lo
• Allele ID: MGI:5437079
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrp1^b2b1554Clo/Lrp1^b2b1554Clo	C57BL/6J-Lrp1^b2b1554Clo	MGI:5437118

Genotype
MGI:5437118

hm1

• Allelic Composition: Lrp1^b2b1554Clo/Lrp1^b2b1554Clo
• Genetic Background: C57BL/6J-Lrp1^b2b1554Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1554-004-1 (E14.5) exhibits gastroschisis with liver and gut outside the abdominal cavity (celoschisis)

cardiovascular system

atrioventricular septal defect ( J:175213 )

abnormal heart ventricle outflow tract morphology ( J:175213 )

growth/size/body

abnormal body wall morphology ( J:175213 )

• body wall closure defects

herniated abdominal wall ( J:175213 )

omphalocele ( J:175213 )

muscle

diaphragmatic hernia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
congenital diaphragmatic hernia		DOID:3827	OMIM:142340 OMIM:222400 OMIM:610187	J:175213
gastroschisis		DOID:11044	OMIM:230750	J:175213
omphalocele		DOID:0060327	OMIM:164750	J:175213