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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhbdf2m1Btlr
mutation 1, Bruce Beutler
MGI:5437475
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rhbdf2m1Btlr/Rhbdf2m1Btlr C57BL/6J-Rhbdf2m1Btlr MGI:5437487
ht2
 		Rhbdf2m1Btlr/Rhbdf2tm1a(KOMP)Wtsi involves: C57BL/6J * C57BL/6N MGI:5437489


Genotype
MGI:5437487
hm1
Allelic
Composition		 Rhbdf2m1Btlr/Rhbdf2m1Btlr
Genetic
Background		 C57BL/6J-Rhbdf2m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf2m1Btlr mutation (1 available); any Rhbdf2 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:187583 )
• peritoneal macrophage exhibit mildly impaired TLR-induced TNFalpha response




Genotype
MGI:5437489
ht2
Allelic
Composition		 Rhbdf2m1Btlr/Rhbdf2tm1a(KOMP)Wtsi
Genetic
Background		 involves: C57BL/6J * C57BL/6N
Cell Lines EPD0208_1_D12
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf2m1Btlr mutation (1 available); any Rhbdf2 mutation (84 available)
Rhbdf2tm1a(KOMP)Wtsi mutation (1 available); any Rhbdf2 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:187583 )
• peritoneal macrophage exhibit impaired TLR-induced TNFalpha response




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory