Phenotypes associated with this allele

• Allele Symbol: Rab7^tm1.2Ywd
• Allele Name: targeted mutation 1.2, Yoh Wada
• Allele ID: MGI:5437841
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rab7^tm1.2Ywd/Rab7^tm1.2Ywd	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL	MGI:5438009

Genotype
MGI:5438009

hm1

• Allelic Composition: Rab7^tm1.2Ywd/Rab7^tm1.2Ywd
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

failure to gastrulate ( J:187732 )

• mutant embryos fail to complete gastrulation

abnormal primitive streak elongation ( J:187732 )

• mutant embryos fail to elongate the primitive streak along the midline

abnormal visceral endoderm morphology ( J:187732 )

• lack large apical vacuoles with smaller, fragmented vesicles