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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rasl10btm1Eno
targeted mutation 1, Eric N Olson
MGI:5437949
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rasl10btm1Eno/Rasl10btm1Eno involves: 129S/SvEv * C57BL/6 MGI:5437950


Genotype
MGI:5437950
hm1
Allelic
Composition		 Rasl10btm1Eno/Rasl10btm1Eno
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rasl10btm1Eno mutation (0 available); any Rasl10b mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell morphology ( J:187574 )
• large dense-core vescicles of atrial cells are smaller than those of atrial cells from controls
abnormal vesicle-mediated transport ( J:187574 )
• cardiomyocytes challenged with hypotonic buffer release only 10-20% of stored ANP compared to 50-60% released by controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory