Phenotypes associated with this allele

• Allele Symbol: Cep290^b2b1752Clo
• Allele Name: Bench to Bassinet Program (B2B/CVDC), mutation 1752 Cecilia Lo
• Allele ID: MGI:5438068
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep290^b2b1752Clo/Cep290^b2b1752Clo	C57BL/6J-Cep290^b2b1752Clo	MGI:5442145

Genotype
MGI:5442145

hm1

• Allelic Composition: Cep290^b2b1752Clo/Cep290^b2b1752Clo
• Genetic Background: C57BL/6J-Cep290^b2b1752Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1752-002-LA displays heterotaxy indicated by mesocardia, left lung isomerism and dextrogastria

cardiovascular system

d-loop transposition of the great arteries ( J:175213 )

atrial septal defect ( J:175213 )

atrioventricular septal defect ( J:175213 )

ventricular septal defect ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

hematopoietic system

spleen hypoplasia ( J:175213 )

immune system

spleen hypoplasia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213