All Phenotypes Rnf212<tm1Nhtr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rnf212^tm1Nhtr
targeted mutation 1, Neil Hunter
MGI:5438282

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf212^tm1Nhtr/Rnf212^tm1Nhtr	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:5438289

Allelic Composition	Rnf212^tm1Nhtr/Rnf212^tm1Nhtr
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf212^tm1Nhtr mutation (1 available); any Rnf212 mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal male meiosis ( J:187173 )

• synaptonemal complexes fail to initiate between centromeres

• crossing over is reduced greater than 95%

• spermatocytes lack chiasmata and exhibit crossover defects

cellular

abnormal male meiosis ( J:187173 )

• synaptonemal complexes fail to initiate between centromeres

• crossing over is reduced greater than 95%

• spermatocytes lack chiasmata and exhibit crossover defects

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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