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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rnf212tm1Nhtr
targeted mutation 1, Neil Hunter
MGI:5438282
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rnf212tm1Nhtr/Rnf212tm1Nhtr involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:5438289


Genotype
MGI:5438289
hm1
Allelic
Composition		 Rnf212tm1Nhtr/Rnf212tm1Nhtr
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf212tm1Nhtr mutation (1 available); any Rnf212 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:187173 )
• synaptonemal complexes fail to initiate between centromeres
• crossing over is reduced greater than 95%
• spermatocytes lack chiasmata and exhibit crossover defects

cellular
abnormal male meiosis ( J:187173 )
• synaptonemal complexes fail to initiate between centromeres
• crossing over is reduced greater than 95%
• spermatocytes lack chiasmata and exhibit crossover defects




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory