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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Plk3tm1Elan
targeted mutation 1, Elan Pharmaceuticals Inc
MGI:5438531
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Plk3tm1Elan/Plk3tm1Elan C57BL/6-Plk3tm1Elan MGI:5438533
hm2
 		Plk3tm1Elan/Plk3tm1Elan involves: 129S6/SvEvTac * C57BL/6 MGI:5438532


Genotype
MGI:5438533
hm1
Allelic
Composition		 Plk3tm1Elan/Plk3tm1Elan
Genetic
Background		 C57BL/6-Plk3tm1Elan
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plk3tm1Elan mutation (1 available); any Plk3 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality, complete penetrance ( J:201467 )
• Background Sensitivity: unlike on a mixed 129S6/SvEvTac and C57BL/6 background on which mice are viable




Genotype
MGI:5438532
hm2
Allelic
Composition		 Plk3tm1Elan/Plk3tm1Elan
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plk3tm1Elan mutation (1 available); any Plk3 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:201467 )
N
• Background Sensitivity: mice are viable unlike when backcrossed on a mixed 129S6/SvEvTac and C57BL/6 background




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory