Phenotypes associated with this allele

• Allele Symbol: Nos3^tm1.2Taka
• Allele Name: targeted mutation 1.2, Takamune Takahashi
• Allele ID: MGI:5438595
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nos3^tm1.2Taka/Nos3^tm1.2Taka	involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA	MGI:5438598

Genotype
MGI:5438598

hm1

• Allelic Composition: Nos3^tm1.2Taka/Nos3^tm1.2Taka
• Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased heart rate ( J:187860 )

increased mean systemic arterial blood pressure ( J:187860 )

increased systemic arterial systolic blood pressure ( J:187860 )

renal/urinary system

abnormal renal glomerulus morphology ( J:187860 )

• thrombotic glomerular lesions and focal renal scars containing crowded atubular glomeruli in most mice

• thrombotic/mesangiolytic glomeruli in some mice

decreased kidney weight ( J:187860 )

homeostasis/metabolism

increased circulating glucose level ( J:187860 )

♀

increased circulating triglyceride level ( J:187860 )

♂