Analysis Tools
hematopoietic system
| N |
• young mice exhibit a normal hematopoietic system
|
|
• at 12 to 14 months in some mice
|
|
• some older mice develop a low-penetrant, cell-intrinsic hematopoietic disorder
|
|
• some mice exhibit myeloid-biased differentiation at 18 to 24 months
|
|
• reduced levels of granulocyte-monocyte progenitors (GMP) and increase in preMegEs in some mice at 12 months
|
|
• at 12 to 14 months in the bone marrow of some mice
|
|
• slight at 12 to 14 months in the bone marrow of some mice
|
|
• at 12 to 14 months in the bone marrow of some mice
|
immune system
|
• at 12 to 14 months in some mice
|
|
• some mice exhibit myeloid-biased differentiation at 18 to 24 months
|
|
• slight at 12 to 14 months in the bone marrow of some mice
|
growth/size/body
|
• at 12 to 14 months in some mice
|
