mortality/aging
• in mice treated with a high does tamoxifen induction regime
|
liver/biliary system
liver cyst
(
J:188763
)
• bile duct-derived cysts in the liver beginning at P28 in tamoxifen-treated mice
• severe by 4 to 5 months in tamoxifen-treated mice
• expression of Tg(Pkd2)#Som expression does not rescue cystic liver phenotype
• however, expression of Tg(Pdk1)248Som rescues cystic liver phenotype
|
growth/size/body
liver cyst
(
J:188763
)
• bile duct-derived cysts in the liver beginning at P28 in tamoxifen-treated mice
• severe by 4 to 5 months in tamoxifen-treated mice
• expression of Tg(Pkd2)#Som expression does not rescue cystic liver phenotype
• however, expression of Tg(Pdk1)248Som rescues cystic liver phenotype
|