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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mgat5btm1.1Itl
targeted mutation 1.1, inGenious Targeting Laboratory
MGI:5442815
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mgat5btm1.1Itl/Mgat5btm1.1Itl involves: C57BL/6 MGI:5443813
cx2
Mgat5tm1Jwd/Mgat5tm1Jwd
Mgat5btm1.1Itl/Mgat5btm1.1Itl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5443814


Genotype
MGI:5443813
hm1
Allelic
Composition
Mgat5btm1.1Itl/Mgat5btm1.1Itl
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mgat5btm1.1Itl mutation (0 available); any Mgat5b mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice exhibit low levels of O-man-linked beta1,6-branched glycans
• however, mice exhibit normal levels of N-linked beta1,6-branched glycans




Genotype
MGI:5443814
cx2
Allelic
Composition
Mgat5tm1Jwd/Mgat5tm1Jwd
Mgat5btm1.1Itl/Mgat5btm1.1Itl
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mgat5btm1.1Itl mutation (0 available); any Mgat5b mutation (66 available)
Mgat5tm1Jwd mutation (1 available); any Mgat5 mutation (63 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice exhibit total loss of N-linked and O-man-linked beta1,6-branched glycans

nervous system
N
• mice exhibit normal neural development and function





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory