All Phenotypes Nostrin<tm1Oess> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nostrin^tm1Oess
targeted mutation 1, Stefanie Oess
MGI:5444008

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Nostrin^tm1Oess/Nostrin^tm1Oess Tg(Tek-cre)12Flv/0	involves: 129S2/SvPas * C3H * C57BL/6	MGI:5444445

Allelic Composition	Nostrin^tm1Oess/Nostrin^tm1Oess Tg(Tek-cre)12Flv/0
Genetic Background	involves: 129S2/SvPas * C3H * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nostrin^tm1Oess mutation (0 available); any Nostrin mutation (37 available)
Tg(Tek-cre)12Flv mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal vascular endothelial cell migration ( J:188414 )

• vascular endothelial cells in the retina exhibit reduced migration with reduced number of filopodia at the leading edge of the expanding vascular plexus compared to in wild-type mice

decreased vascular endothelial cell proliferation ( J:188414 )

• vascular endothelial cells in the retina exhibit reduced proliferation

cellular

abnormal vascular endothelial cell migration ( J:188414 )

• vascular endothelial cells in the retina exhibit reduced migration with reduced number of filopodia at the leading edge of the expanding vascular plexus compared to in wild-type mice

decreased vascular endothelial cell proliferation ( J:188414 )

• vascular endothelial cells in the retina exhibit reduced proliferation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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