Phenotypes associated with this allele

• Allele Symbol: Nat8l^tm1Atni
• Allele Name: targeted mutation 1, Atsumi Nitta
• Allele ID: MGI:5444021
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nat8l^tm1Atni/Nat8l^tm1Atni	involves: C57BL/6J	MGI:5444022

Genotype
MGI:5444022

hm1

• Allelic Composition: Nat8l^tm1Atni/Nat8l^tm1Atni
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal response to novelty ( J:188917 )

• in a novel environment mutant mice do not actively investigate a novel mouse and are largely submissive to the novel mouse unlike wild-type controls

abnormal habituation to a novel object ( J:188917 )

• the exploration time of novel objects in the acquisition phase of the novel object recognition test is significantly longer

increased grooming behavior ( J:188917 )

• increase in grooming time in an open field assay

increased vertical activity ( J:188917 )

• increase in rearing time in an open field assay

decreased locomotor activity ( J:188917 )

• decrease in the distance traveled in an open field assay

abnormal social investigation ( J:188917 )

• in a novel environment mutant mice do not actively investigate a novel mouse and are largely submissive to the novel mouse unlike wild-type controls

• however, interactions of mutant mice with a novel mouse that take place in their home cage are similar controls