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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccr2tm1Mpa
targeted mutation 1, Manolis Pasparakis
MGI:5444249
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ccr2tm1Mpa/Ccr2tm1Mpa
Lyz2tm1(cre)Ifo/Lyz2+ 		involves: 129P2/OlaHsd * C57BL/6 * CBA MGI:5444292


Genotype
MGI:5444292
cn1
Allelic
Composition		 Ccr2tm1Mpa/Ccr2tm1Mpa
Lyz2tm1(cre)Ifo/Lyz2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr2tm1Mpa mutation (0 available); any Ccr2 mutation (43 available)
Lyz2tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased macrophage cell number ( J:189044 )
• 7 days after skin wound injury

homeostasis/metabolism
abnormal wound healing ( J:189044 )
• 7 days after skin wound injury, mice exhibit reduced macrophage compared with control mice
• however, the rate of wound closure is normal

immune system
decreased macrophage cell number ( J:189044 )
• 7 days after skin wound injury




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory