All Phenotypes Ccr2<tm1.1Mpa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ccr2^tm1.1Mpa
targeted mutation 1.1, Manolis Pasparakis
MGI:5444250

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccr2^tm1.1Mpa/Ccr2^tm1.1Mpa	involves: BALB/cJ * C57BL/6	MGI:5444291

Allelic Composition	Ccr2^tm1.1Mpa/Ccr2^tm1.1Mpa
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr2^tm1.1Mpa mutation (0 available); any Ccr2 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

decreased macrophage cell number ( J:189044 )

• 7 days after skin wound injury

decreased monocyte cell number ( J:189044 )

• in unwounded mice

homeostasis/metabolism

abnormal wound healing ( J:189044 )

• 7 days after skin wound injury, mice exhibit reduced macrophage compared with control mice

• however, the rate of wound closure is normal

immune system

decreased macrophage cell number ( J:189044 )

• 7 days after skin wound injury

decreased monocyte cell number ( J:189044 )

• in unwounded mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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