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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map2k7tm1Pngr
targeted mutation 1, Josef M Penninger
MGI:5444459
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Map2k7tm1Pngr/Map2k7+ involves: 129P2/OlaHsd * C57BL/6J MGI:5444462


Genotype
MGI:5444462
ht1
Allelic
Composition		 Map2k7tm1Pngr/Map2k7+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map2k7tm1Pngr mutation (0 available); any Map2k7 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal spatial working memory ( J:188339 )
• make fewer correct responses and show increased perseverative errors in a discrete paired-trial variable delay T-maze working memory assay
• however, locomotor activity in an open field is similar to controls

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
schizophrenia DOID:5419 OMIM:181500
 J:188339




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory