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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sftpctm1(cre/ERT2,rtTA)Hap
targeted mutation 2, Harold A Chapman
MGI:5444645
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mettm1Sst/Mettm1Sst
Sftpctm1(cre/ERT2,rtTA)Hap/Sftpc+ 		involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N MGI:6197801


Genotype
MGI:6197801
cn1
Allelic
Composition		 Mettm1Sst/Mettm1Sst
Sftpctm1(cre/ERT2,rtTA)Hap/Sftpc+
Genetic
Background		 involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettm1Sst mutation (1 available); any Met mutation (83 available)
Sftpctm1(cre/ERT2,rtTA)Hap mutation (0 available); any Sftpc mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
abnormal pulmonary alveolus morphology ( J:264185 )
• tamoxifen-treated mice show reduced density of alveoli
overexpanded pulmonary alveolus ( J:264185 )
• alveoli are enlarged in tamoxifen-treated mice
emphysema ( J:264185 )
• adult mice treated with tamoxifen exhibit enlargement of alveolar airspace and loss of alveolar density, indicating emphysematous changes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory