immune system
N |
• enforced expression of human MYC rescues germinal center formation
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Allele Symbol Allele Name Allele ID |
Gt(ROSA)26Sortm13(CAG-MYC,-CD2*)Rsky targeted mutation 13, Klaus Rajewsky MGI:5444670 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• enforced expression of human MYC rescues germinal center formation
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• when bone marrow is used to reconstitute Rag2 and Il2rg null mice stimulated with sheep red blood cells, median survival is 227 days
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• impaired
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• in the Peyer's patches and spleen
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• of germinal center B cell origin when bone marrow is used to reconstitute Rag2 and Il2rg null mice stimulated with sheep red blood cells
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• impaired
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• in the Peyer's patches and spleen
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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